![]() The collagen fibrils were observed using a scanning electronic microscope. In this study, we investigated chondrogenic differentiation of human mesenchymal stem cells (hMSCs) cultured on tilapia scale collagen fibrils compared with porcine collagen and non-coated dishes. Among fish collagens, tilapia collagen, the denaturing temperature of which is near 37Â☌, is appropriate for cell and tissue culture. Fish collagen could overcome the risk of zoonosis, such as from bovine spongiform encephalopathy. ![]() ![]() Hsu, Han-Hsiu Uemura, Toshimasa Yamaguchi, Isamu Ikoma, Toshiyuki Tanaka, Junzoįish collagen has recently been reported to be a novel biomaterial for cell and tissue culture as an alternative to conventional mammalian collagens such as bovine and porcine collagens. Chondrogenic differentiation of human mesenchymal stem cells on fish scale collagen. ![]()
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